Summary: CD36 promoter SNP allele –22674C is therefore associated with lower serum low-density lipoprotein-cholesterol in normal female twins and with improved lipid profile during weight loss and maintenance in obese subjects.

Summary: The Pro12Ala PPARG polymorphism interacted with Polyunsaturated Fats intake on myocardial infarction. The protective effect of Polyunsaturated Fats intake was attenuated in carriers of the Ala12 allele. OR (95% CI) for myocardial infarction per each 5% increase in energy from polyunsaturated fat were 0.66 (0.53, 0.82) in Pro12/Pro12 subjects and 0.93 (0.61, 1.42) in carriers of the Ala12 allele.